反应详情

温度

130 °C

The mixture of 0.26 g (0.8 mmol) of 6-chloro-2-(4-fluorophenyl)-3-(pyridazin-4-yl)imidazo[1,2-b]pyridazine and 0.66 g (3.2 mmol) of 1-isopropylpiperazine in 6 ml of pentanol is heated in a sealed tube at 130° C. for 10 hours.