HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methylethylamine → 5-chloro-N-ethyl-N-methylpyrazine-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methylethylamine | HCID 12219 | — |
| Reactant | 5-Chloropyrazinoic acid | HCID 465472 | — |
| Product | 5-chloro-N-ethyl-N-methylpyrazine-2-carboxamide | HCID 59483312 | 81.4% |
Reaction Steps
The title compound (I-7a) was prepared by a method analogous to that described for the preparation of SM-1 using 5-chloropyrazine-2-carboxylic acid (2 g, 12.62 mmol) and ethyl-methyl-amine (0.846 g, 13.9 mmol) to afford the title compound 5-chloro-N-ethyl-N-methylpyrazine-2-carboxamide (SM-4: 2.05 g, 81%) as a clear oil
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08455496B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-1e0aab2bcd54469f8a5d5ac67521a902 |
| Source note | uspto-grants-2013_06 |