HuagongsheHuagongshe Chemistry Print Report · For research reference only
7379-35-3 → 7-(Pyridin-4-yl)-2,7-diazaspiro[3.5]nonane dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7379-35-3 | HCID 10877290 | — |
| Reactant | tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate | HCID 23282935 | — |
| Product | 7-(Pyridin-4-yl)-2,7-diazaspiro[3.5]nonane dihydrochloride | HCID 67547065 | — |
Reaction Steps
The synthesis was carried out analogously to the synthesis of amine AMN-07. For this, in step (i) tert-butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate was reacted with 4-chloropyridinium chloride and in step (ii) the Boc protective group was split off in order to obtain the amine AMN-08.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08455475B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-f556812706244fe1b7b608004876809f |
| Source note | uspto-grants-2013_06 |