Nicotinic Acid → N-[5-cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-yl]-nicotinamide

Participants

Reaction Steps

This compound was prepared following the same procedure as described for Example 3 using 5-cyclopentyl-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine (Example 1c) (100 mg, 0.38 mmol) and nicotinic acid (40.6 mg, 0.33 mmol) as starting materials. The title compound (61 mg, 43.3%) was isolated as off white solid; MS (ESI): 366 [M+H]+.

Provenance & Evidence