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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1253787Generated: October 25, 2026

5-Cyclohexyl-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine → HCID 178426984, compound

https://huagongshe.com/reaction/1253787

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Cyclohexyl-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamineHCID 71294148—
ReactantHCID 178427254HCID 178427254—
ProductHCID 178426984HCID 17842698453.1%

Reaction Steps

This compound was prepared following the same procedure as described for Example 3 using 5-cyclohexyl-6-(2,2,2-trifluoro-ethoxy)-pyridin-3-ylamine (Example 8b) (100 mg, 0.36 mmol) and 5-methyl-2H-pyrazole-3-carboxylic acid (40.6 mg, 0.33 mmol) as starting materials. The title compound (67 mg, 48.2%) was isolated as off white solid; MS (ESI): 383 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08455501B2
Source datasetuspto-grants-2013_06
ORD IDord-c23e62db8f3c44d395891d3eb44a4791
Source noteuspto-grants-2013_06