Ammonia → HCID 10490937, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of methyl 5-bromo-4-chloro-2-hydroxybenzoate (2.655 g, 10.00 mmol) in a solution of ammonia (50.0 ml, 100 mmol) in MeOH was heated at 65° C. for 72 hr. After concentration, the title product was obtained as solid (2.53 g). ESI-MS m/z: 252.1 [M+1]+, Retention time 1.19 min; 1HNMR (CDCl3, 400.342 MHz) δ 7.15 (s, 1H), 7.61 (s, 1H), 12.2 (brs, 1H).

Provenance & Evidence