Hydrochloric Acid → HCID 178510666, compound

Participants

Reaction Conditions

Reaction Steps

To a stirred solution of the product obtained in Step E (250 mg, 0.686 mmol) in EtOH (4 mL) was added 1N HCl (8 mL). The resulting mixture was heated at 90° C. under nitrogen for 3 h. Solvents were removed and the crude product was subjected to column chromatography on a silica gel Biotage 40S® column, eluting with 5 to 14% MeOH (containing 10% conc. NH4OH) in CH2Cl2 to give the title compound. LC-MS: 135.1 (M+H).

Provenance & Evidence