HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminium lithium hydride → HCID 24765214, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | HCID 24765116 | HCID 24765116 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 24765214 | HCID 24765214 | 92% |
Reaction Steps
The title compound was prepared by reducing Methyl 2-(2,6-difluorobenzamido)-5-(3-fluorophenyl)thiazole-4-carboxylate with lithium aluminum hydride (2 equiv) in THF. Yield: 92%. H-NMR(CDCl3) 7.50-6.90 (7H, m), 4.60 (2H, s). MS (ESI) [MH+] 365.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08455658B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-96f740ad907c493d84413842738e68ff |
| Source note | uspto-grants-2013_06 |