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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1255126Generated: October 25, 2026

N-(5-(Benzo[d][1,3]dioxol-5-yl)-4-methylthiazol-2-yl)-2,6-difluorobenzamide → 2,6-Difluoro-N-(4-methyl-5-(thiophen-3-yl)thiazol-2-yl)benzamide

https://huagongshe.com/reaction/1255126

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(5-(Benzo[d][1,3]dioxol-5-yl)-4-methylthiazol-2-yl)-2,6-difluorobenzamideHCID 24765406—
ReactantN-(5-(2,5-Dibromothiophen-3-yl)-4-methylthiazol-2-yl)-2,6-difluorobenzamideHCID 24765485—
Product2,6-Difluoro-N-(4-methyl-5-(thiophen-3-yl)thiazol-2-yl)benzamideHCID 24765486—

Reaction Steps

Compound 62 was prepared from was prepared from Compound 61 as described for the preparation of Compound 57.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08455658B2
Source datasetuspto-grants-2013_06
ORD IDord-448f23d8e2f34156a4da88827ded41df
Source noteuspto-grants-2013_06