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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1255138Generated: November 1, 2026

2,6-difluoro-N-(4-(prop-1-en-2-yl)-5-(3-(trifluoromethyl)phenyl)thiazol-2-yl)benzamide → 2,6-Difluoro-N-(5-(3-(trifluoromethyl)phenyl)-4-vinylthiazol-2-yl)benzamide

https://huagongshe.com/reaction/1255138

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,6-difluoro-N-(4-(prop-1-en-2-yl)-5-(3-(trifluoromethyl)phenyl)thiazol-2-yl)benzamideHCID 24765579—
Reactant2,6-Difluoro-N-(4-(1-hydroxyethyl)-5-(3-(trifluoromethyl)phenyl)thiazol-2-yl)benzamideHCID 59004555—
Product2,6-Difluoro-N-(5-(3-(trifluoromethyl)phenyl)-4-vinylthiazol-2-yl)benzamideHCID 24765581—

Reaction Steps

Compound 75 was prepared from Compound 74 similarly as described for the preparation of Compound 68a.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08455658B2
Source datasetuspto-grants-2013_06
ORD IDord-a5d277754c194604a157111c2a4005c6
Source noteuspto-grants-2013_06