HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-ethoxy-2-thioxoAcetamide → Ethyl 2'-(2,6-difluorobenzamido)-5'-(3-(trifluoromethyl)phenyl)-4,4'-bithiazole-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-ethoxy-2-thioxoAcetamide | HCID 21613763 | — |
| Reactant | N-(4-(2-Bromoacetyl)-5-(3-(trifluoromethyl)phenyl)thiazol-2-yl)-2,6-difluorobenzamide | HCID 24765772 | — |
| Reactant | 2,6-Difluoro-N-(2'-methyl-5-(3-(trifluoromethyl)phenyl)-4,4'-bithiazol-2-yl)benzamide | HCID 59004499 | — |
| Product | Ethyl 2'-(2,6-difluorobenzamido)-5'-(3-(trifluoromethyl)phenyl)-4,4'-bithiazole-2-carboxylate | HCID 59004509 | — |
Reaction Steps
Compound 88 was prepared from Compound 85 and ethyl thiooxamate similarly as described for the preparation of Compound 86.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08455658B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-51c2a2fc33c94082afa26ffeffa7e828 |
| Source note | uspto-grants-2013_06 |