HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2,6-Difluorobenzamido)-5-(3-(trifluoromethyl)phenyl)thiazole-4-carboxylic acid → 2-(3-Methylisonicotinamido)-5-(3-(trifluoromethyl)phenyl)thiazole-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2,6-Difluorobenzamido)-5-(3-(trifluoromethyl)phenyl)thiazole-4-carboxylic acid | HCID 59004486 | — |
| Reactant | Methyl 2-(3-methylisonicotinamido)-5-(3-(trifluoromethyl)phenyl)thiazole-4-carboxylate hydrochloride | HCID 86761875 | — |
| Product | 2-(3-Methylisonicotinamido)-5-(3-(trifluoromethyl)phenyl)thiazole-4-carboxylic acid | HCID 59004510 | — |
Reaction Steps
Compound 112 was prepared from Compound 111 by hydrolysis similarly as described for the preparation of Compound 66.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08455658B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-834d54e4c8724dc18723c03aa88c1860 |
| Source note | uspto-grants-2013_06 |