[3-Methyl-4'-(trifluoromethyl)biphenyl-4-yl]methanol → 1-(5'-Chloro-2'-{[3-methyl-4'-(trifluoromethyl)biphenyl-4-yl]methoxy}-2,3'-bipyridin-6-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid

Participants

Reaction Steps

The title compound was prepared according to the procedure described in Example 237 Step B, by reaction of the title compound from Example 239 Step A with [3-methyl-4′-(trifluoromethyl)biphenyl-4-yl]methanol (PCT Publication WO2005118542): LCMS m/z 632.7 [M+H]+; 1H NMR (500 MHz, acetone-d6) δ 8.22 (m, 2H), 7.92 (d, J=8.2 Hz, 2H), 7.83 (m, 3H), 7.63 (m, 2H), 5.70 (s, 2H), 2.52 (s, 3H).

Provenance & Evidence