Propylamine → HCID 59229765, compound

HRID 1255422Notes

Reaction equation

[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[CH:7][NH:8][C:9]2=[O:12])=[CH:4][C:3]=1[O:13][CH:14]1[CH2:19][CH2:18][N:17]([CH2:20][C:21]([N:23](C)[CH3:24])=[O:22])[CH2:16][CH2:15]1.[CH2:26](N)[CH2:27]C>>[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[CH:7][NH:8][C:9]2=[O:12])=[CH:4][C:3]=1[O:13][CH:14]1[CH2:15][CH2:16][N:17]([CH2:20][C:21]([NH:23][CH2:24][CH2:26][CH3:27])=[O:22])[CH2:18][CH2:19]1

Participants

Reactant 2

HCID 7852Propylamine

HCID 59229770HCID 59229770, compound

Product 1

HCID 59229765HCID 59229765, compound

Procedure

The title compound was synthesized following the method described for 2-[4-(7-Chloro-1-oxo-1,2-dihydro-isoquinolin-6-yloxy)-piperidin-1-yl]-acetamide (43), using propylamine. Rt=0.98 min (Method B). Detected mass: 378.2 (M+H+).

Sources & evidence

ORD record: ord-75055962603741deb60328b3548fcbf2
Source dataset: uspto-grants-2013_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08461144B2

Reaction notes

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