HRID1255523

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COC(=O)[C@@H]1C[C@@H](Oc2cccc(OCc3ccccc3)n2)CN1C(=O)OC(C)(C)C

HCID58158086

未命名化合物

PRODUCTS

生成物

结构：COC(=O)[C@@H]1C[C@@H](Oc2cccc(O)n2)CN1C(=O)OC(C)(C)C

HCID178501329

未命名化合物

收率 96%

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID23938

Palladium

溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

A Parr jar was charged with the product of Step 3 (6.50 g, 15.17 mmol), EtOH (100 ml), and 10% Pd/C (0.250 g, 2.349 mmol). Hydrogenated at 48 psi. Reaction complete after 18 hours. Filtered through celite. Evaporation of the filtrate gave the title compound as a white foam. (4.95 g, 14.63 mmol, 96% yield). LCMS (ES+) m/z 339.3 (M+H)+.

WORKUP

后处理

customReaction complete after 18 hours
filtrationFiltered through celite
customEvaporation of the filtrate