1-tert-Butyl 2-methyl (2S,4R)-4-{[6-(benzyloxy)pyridin-2-yl]oxy}pyrrolidine-1,2-dicarboxylate → HCID 178501329, compound

Participants

Reaction Steps

A Parr jar was charged with the product of Step 3 (6.50 g, 15.17 mmol), EtOH (100 ml), and 10% Pd/C (0.250 g, 2.349 mmol). Hydrogenated at 48 psi. Reaction complete after 18 hours. Filtered through celite. Evaporation of the filtrate gave the title compound as a white foam. (4.95 g, 14.63 mmol, 96% yield). LCMS (ES+) m/z 339.3 (M+H)+.

Provenance & Evidence