Hydrochloric Acid → (2S,4R)-4-[(1-Allyl-6-oxo-1,6-dihydropyridin-2-yl)oxy]-2-(methoxycarbonyl)-pyrrolidinium chloride

Participants

Reaction Steps

A 100 mL round bottom flask was charged with the product of Step 6 (1.91 g, 5.05 mmol). Added HCl (4.0M in dioxane) (30 mL, 120 mmol). Stirred at room temperature for 1 hour. Evaporated. Added ethanol. Evaporated. Repeated. The title compound remained as a pale foam. (1.59 g, 5.05 mmol, 100% yield). LCMS (ES+) m/z 279.3 (M+H)+.

Provenance & Evidence