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HRID1255784

反应详情

EQUATION

反应方程式

HRID 1255784 的结构方程式

REACTANTS

反应物

2
结构：CNC(=S)NC(=O)OC(C)(C)C
HCID57496573

tert-Butyl (methylcarbamothioyl)carbamate

C7H14N2O2S

结构：COC(=O)C[C@](C)(N)c1cc([N+](=O)[O-])ccc1F
HCID57505083

未命名化合物

PRODUCTS

生成物

1
结构：CN1C(=O)C[C@@](C)(c2cc([N+](=O)[O-])ccc2F)N=C1NC(=O)OC(C)(C)C
HCID57501006

未命名化合物

PROCEDURE

实验过程

Starting from (S)-3-amino-3-(2-fluoro-5-nitro-phenyl)-butyric acid methyl ester (14.8 mmole) and tert-butyl [(methylamino)carbonothioyl]carbamate, the product [(S)-4-(2-fluoro-5-nitro-phenyl)-1,4-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyrimidin-2-yl]-carbamic acid tert-butyl ester (3.13 g) was obtained as pale yellow foam. MS (ESI): m/z=381.2 [ M+H]+.