Sulfuric Acid → HCID 17953125, compound

Participants

Reaction Conditions

Reaction Steps

(5-Bromo-pyridin-3-yl)-acetonitrile (1 g, 5.1 mmol) was dissolved in a mixture of EtOH (20 ml) and water (1.2 ml). H2SO4 (6.8 ml) was then added to the mixture and the mixture was heated at −110° C. for 24 hrs. Solvent was removed under vacuo, taken up in EtOAc and washed with 2N Na2CO3 solution. Drying and evaporation gave a crude oil which was sufficiently pure for the next step.

Provenance & Evidence