HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetyl chloride → HCID 15984041, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetyl chloride | HCID 6577 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | HCID 24960475 | HCID 24960475 | — |
| Reactant | HCID 86618846 | HCID 86618846 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 15984041 | HCID 15984041 | — |
Reaction Steps
Compound 1b was prepared as described hereinabove for Compound 1a, using Compound 38b (0.085 gram, 0.16 mmol), DIPEA (0.33 mmol, 57.8 μl) and chloroacetylchloride (0.33 mmol, 26.4 μ) in THF (11 ml), as starting materials, to give 0.025 gram (26% yield) of the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08461166B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-02f231d9598445cfbb9f9ce7c54cfe3c |
| Source note | uspto-grants-2013_06 |