Indole → 3-(2,5-Dichloropyrimidin-4-yl)-1H-indole
Reaction equation
[Cl:1][C:2]1[N:7]=[C:6](Cl)[C:5]([Cl:9])=[CH:4][N:3]=1.[NH:10]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=[CH:11]1>>[Cl:1][C:2]1[N:7]=[C:6]([C:12]2[C:13]3[C:18](=[CH:17][CH:16]=[CH:15][CH:14]=3)[NH:10][CH:11]=2)[C:5]([Cl:9])=[CH:4][N:3]=1Participants
3
Procedure
Starting materials: 2,4,5-trichloropyrimidine and 1H-indole. m/z 265.
Sources & evidence
- ORD record
- ord-72f5c4176bfa4b3793faca8aca439103
- Source dataset
- uspto-grants-2013_06
- Patent number
- US08461170B2
Reaction notes
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