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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1256006Generated: October 30, 2026

3-Fluoropyrrolidine → (R)-4-(3-Fluoropyrrolidin-1-yl)-1-(3-methoxy-4-nitrophenyl)piperidine

https://huagongshe.com/reaction/1256006

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-FluoropyrrolidineHCID 2759163—
Reactant1-(3-Methoxy-4-nitrophenyl)piperidin-4-oneHCID 25918857—
Product(R)-4-(3-Fluoropyrrolidin-1-yl)-1-(3-methoxy-4-nitrophenyl)piperidineHCID 58071437—

Reaction Steps

Starting materials: 1-(3-methoxy-4-nitrophenyl)piperidin-4-one (INTERMEDIATE 18) and (R)-3-fluoropyrrolidine. m/z 324.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08461170B2
Source datasetuspto-grants-2013_06
ORD IDord-4ba98812076744dabb9abd192f680e6f
Source noteuspto-grants-2013_06