Lithium hydroxide, monohydrate → HCID 24887408, compound

Participants

Reaction Steps

To a magnetically stirred solution of ethyl 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylsulfanyl-1H-pyrazole-3-carboxylate (4.9 g, 11 mmol) in tetrahydrofuran (100 ml) was added LiOH.H2O (0.47 gram, 11 mmol) and the resulting mixture was reacted for 20 hours at 35° C. and subsequently concentrated in vacuo. The obtained crude lithium 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylsulfanyl-1H-pyrazole-3-carboxylate was used in the next step.

Provenance & Evidence