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HRID1257125

反应详情

EQUATION

反应方程式

HRID 1257125 的结构方程式

REACTANTS

反应物

2
结构：CCOC(C)=O.Cl
HCID21866389

未命名化合物

结构：CC(C)(C)OC(=O)N1CCN(Cc2ccnc(Nc3cc4ccccc4cn3)c2)CC1
HCID67175602

未命名化合物

PRODUCTS

生成物

1
结构：c1ccc2cc(Nc3cc(CN4CCNCC4)ccn3)ncc2c1
HCID44612469

N-[4-(1-Piperazinylmethyl)-2-pyridinyl]-3-isoquinolinamine

C19H21N5

PROCEDURE

实验过程

2-(Isoquinolin-3-ylamino)-4-(4-tert-butoxycarbonylpiperazin-1-ylmethyl)-pyridine was treated with 8 M HCl/EtOAc to afford the title compound as a salt in near quantitative yield (50 mg). 1H NMR (CDCl3, 300 MHz) δ: 3.44 (s, 4H, PyridylCH2NCH2CH2), 3.45 (s, 4H, NHCH2), 4.25 (s, 2H, pyridylCH2), 7.01-8.87 (m, 9H, isoquinolyl+pyridyl).