HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-1-(3,4-dichlorophenyl)ethanone → ethyl 1-{[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]methyl}-1H-pyrazole-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-1-(3,4-dichlorophenyl)ethanone | HCID 244751 | — |
| Reactant | Ethyl 1-(carbamothioylmethyl)-1H-pyrazole-4-carboxylate | HCID 58127901 | — |
| Product | ethyl 1-{[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]methyl}-1H-pyrazole-4-carboxylate | HCID 58127686 | 76% |
Reaction Steps
By a reaction in the same manner as in Example 1c and using the compound (213 mg, 1.00 mmol) obtained in Example 1b and 2-bromo-1-(3,4-dichlorophenyl)ethanone (268 mg, 1.00 mmol) to give the title compound (290 mg, 76%) as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08461348B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-d56655945ce74b019f2d8bab6a5b775b |
| Source note | uspto-grants-2013_06 |