HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromopyruvic Acid → 2-{[4-(ethoxycarbonyl)-1H-pyrazol-1-yl]methyl}-1,3-thiazole-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromopyruvic Acid | HCID 70684 | — |
| Reactant | Ethyl 1-(carbamothioylmethyl)-1H-pyrazole-4-carboxylate | HCID 58127901 | — |
| Product | 2-{[4-(ethoxycarbonyl)-1H-pyrazol-1-yl]methyl}-1,3-thiazole-4-carboxylic acid | HCID 66939248 | 57.9% |
Reaction Steps
By a reaction in the same manner as in Example 1c and using the compound (1.07 g, 5.0 mmol) obtained in Example 1b and bromopyruvic acid (920 mg, 5.5 mmol), the title compound (814 mg, 57%) was obtained as bister crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08461348B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-60ac4ffba9714b88bada35d57757eaab |
| Source note | uspto-grants-2013_06 |