HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → HCID 58127969, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | [4-(ethoxycarbonyl)-1H-pyrazol-1-yl]acetic acid | HCID 59557975 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 58127969 | HCID 58127969 | — |
Reaction Steps
A solution of the compound (2.0 g) obtained in Example 115b in dichloromethane (20 mL) was cooled in an ice bath, and oxalyl chloride (2.5 g) and N,N-dimethylformamide (2 drops) were added. The reaction mixture was stirred at room temperature overnight and the solvent was evaporated under reduced pressure to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08461348B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-8acc7315a6ef47b78335a24e36382fe9 |
| Source note | uspto-grants-2013_06 |