Hydrochloric Acid → HCID 67225149, compound

HRID 1257825Notes

Reaction equation

HRID 1257825 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[O:7][CH2:8][CH2:9][NH:10]C(=O)OC(C)(C)C.[ClH:18]>O1CCOCC1>[ClH:18].[ClH:18].[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[O:7][CH2:8][CH2:9][NH2:10]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 68804906tert-Butyl {2-[(pyridin-2-yl)oxy]ethyl}carbamate

Product 1

HCID 67225149HCID 67225149, compoundYield 96.8%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

tert-Butyl 2-(pyridin-2-yloxy)ethylcarbamate (0.353 g) was treated with 4M of hydrogen chloride in 1,4-dioxane (0.6 mL) at RT for 1 h. The solvent was evaporated under reduced pressure. The residue was washed with ether, and dried to give the desired product (0.30 g, 96.8%).

Workup

  1. customThe solvent was evaporated under reduced pressure
  2. washThe residue was washed with ether
  3. customdried

Sources & evidence

ORD record
ord-275548db9c3040eba0206b621597ead2
Source dataset
uspto-grants-2013_06
Patent number
US08461330B2

Reaction notes

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