Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1257863Generated: November 2, 2026

Methyl iodide → HCID 25145519, compound

https://huagongshe.com/reaction/1257863

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantPotassium CarbonateHCID 11430—
ReactantHCID 67224931HCID 67224931—
SolventDimethylformamideHCID 6228—
ProductHCID 25145519HCID 25145519—

Reaction Steps

To a solution of 6-{1-[6-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrimidin-3-yl]cyclopropyl}quinoline (6 mg, 0.017 mmol) in N,N-dimethylformamide (200 μL) was added potassium carbonate (4.0 mg, 0.029 mmol) and methyl iodide (3 μL, 0.048 mmol). After stirring at RT for 16 h, the reaction mixture was purified by RP-HPLC to afford the desired product. LCMS: (M+H)=367.0.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08461330B2
Source datasetuspto-grants-2013_06
ORD IDord-f5712c7e97b94db4a653f1bb3fcd131b
Source noteuspto-grants-2013_06