Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1257895Generated: November 4, 2026

Trifluoroacetic acid → HCID 67224038, compound

https://huagongshe.com/reaction/1257895

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 67224311HCID 67224311—
SolventDichloromethaneHCID 6344—
ProductHCID 67224038HCID 67224038—

Reaction Steps

Trifluoroacetic Acid (0.5 mL) was added to a solution of tert-butyl 4-{4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]-1H-pyrazol-1-yl}piperidine-1-carboxylate (0.014 g, 0.027 mmol) in methylene chloride (0.5 mL) and stirred at RT for 1 h. The volatiles were removed under reduced pressure and the residue was purified by RP-HPLC (pH 10) to give the desired product. LCMS: (M+H)=411.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08461330B2
Source datasetuspto-grants-2013_06
ORD IDord-f33998f4582d41b797811cf54c0aa848
Source noteuspto-grants-2013_06