Dimethylformamide → Tert-butyl 4-((6-fluoropyridin-3-yl)methyl)piperazine-1-carboxylate

HRID 125825Notes

Reaction equation

HRID 125825 reaction equation
[Br:14][CH2:15][c:16]1[cH:17][cH:18][c:19]([F:22])[n:20][cH:21]1.[CH3:23][N:24]([CH3:25])[CH:26]=[O:27].[N:1]1([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1>>[N:1]1([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:2][CH2:3][N:4]([CH2:15][c:16]2[cH:17][cH:18][c:19]([F:22])[n:20][cH:21]2)[CH2:5][CH2:6]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 143452tert-Butyl piperazine-1-carboxylateHCID 220506385-(Bromomethyl)-2-fluoropyridine

Product 1

HCID 59548414Tert-butyl 4-((6-fluoropyridin-3-yl)methyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-b4467bc98c184f5e889d7e1452905ddd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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