HRID1258392

反应详情

EQUATION

反应方程式

REACTANTS

反应物

$结构：CCSC1=C/C(=N\S(=O)(=O)c2cccs2)c2ccccc2C1=O$

HCID46908089

未命名化合物

结构：Cn1nnnc1Sc1cc(NS(=O)(=O)c2cccs2)c2ccccc2c1O

HCID135895396

未命名化合物

PRODUCTS

生成物

结构：CCSc1cc(NS(=O)(=O)c2cccs2)c2ccccc2c1O

HCID46908186

未命名化合物

HCID135895396

未命名化合物

收率 100%

PROCEDURE

实验过程

N-(3-(ethylthio)-4-hydroxynaphthalen-1-yl)thiophene-2-sulfonamide (14j) was prepared according to the procedure for 14d except using (E)-N-(3-ethylthio-4-oxonaphthalen-1(4H)-ylidene)thiophene-2-sulfonamide (13j), which afforded the title compound 14 mg (100%) as a grey solid, m.p.: ° C.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-9e885f11c8d84d2dbe64937fe0e4deea
来源数据集: uspto-grants-2013_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08466157B2
来源说明: uspto-grants-2013_06

反应 SMILES

[OH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([NH:12][S:13]([C:16]2[S:17][CH:18]=[CH:19][CH:20]=2)(=[O:15])=[O:14])=[CH:4][C:3]=1[S:21][C:22]1[N:26]([CH3:27])[N:25]=[N:24][N:23]=1.[CH2:28]([S:30][C:31]1[C:40](=[O:41])[C:39]2[C:34](=[CH:35][CH:36]=[CH:37][CH:38]=2)/[C:33](=[N:42]/[S:43]([C:46]2[S:47][CH:48]=[CH:49][CH:50]=2)(=[O:45])=[O:44])/[CH:32]=1)[CH3:29]>>[CH2:28]([S:30][C:31]1[CH:32]=[C:33]([NH:42][S:43]([C:46]2[S:47][CH:48]=[CH:49][CH:50]=2)(=[O:44])=[O:45])[C:34]2[C:39]([C:40]=1[OH:41])=[CH:38][CH:37]=[CH:36][CH:35]=2)[CH3:29].[OH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([NH:12][S:13]([C:16]2[S:17][CH:18]=[CH:19][CH:20]=2)(=[O:15])=[O:14])=[CH:4][C:3]=1[S:21][C:22]1[N:26]([CH3:27])[N:25]=[N:24][N:23]=1