HuagongsheHuagongshe Chemistry Print Report · For research reference only
(NE)-N-(3-ethylsulfanyl-4-oxonaphthalen-1-ylidene)thiophene-2-sulfonamide → N-(4-hydroxy-3-(1-methyl-1H-tetrazol-5-ylthio)naphthalen-1-yl)thiophene-2-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (NE)-N-(3-ethylsulfanyl-4-oxonaphthalen-1-ylidene)thiophene-2-sulfonamide | HCID 46908089 | — |
| Reactant | N-(4-hydroxy-3-(1-methyl-1H-tetrazol-5-ylthio)naphthalen-1-yl)thiophene-2-sulfonamide | HCID 135895396 | — |
| Product | N-(3-(ethylthio)-4-hydroxynaphthalen-1-yl)thiophene-2-sulfonamide | HCID 46908186 | — |
| Product | N-(4-hydroxy-3-(1-methyl-1H-tetrazol-5-ylthio)naphthalen-1-yl)thiophene-2-sulfonamide | HCID 135895396 | 100% |
Reaction Steps
N-(3-(ethylthio)-4-hydroxynaphthalen-1-yl)thiophene-2-sulfonamide (14j) was prepared according to the procedure for 14d except using (E)-N-(3-ethylthio-4-oxonaphthalen-1(4H)-ylidene)thiophene-2-sulfonamide (13j), which afforded the title compound 14 mg (100%) as a grey solid, m.p.: ° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08466157B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-9e885f11c8d84d2dbe64937fe0e4deea |
| Source note | uspto-grants-2013_06 |