1-[3-Methoxy-5-(pentafluorosulfanyl)phenyl]ethanone → 1-[3-Bromo-5-(pentafluorosulfanyl)phenyl]ethanone

HRID 1258525Notes

Reaction equation

HRID 1258525 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([CH:11]=[C:12]([S:14]([F:19])([F:18])([F:17])([F:16])[F:15])[CH:13]=1)[C:5](N(OC)C)=[O:6].[CH3:20]OC1C=C(C(=O)C)C=C(S(F)(F)(F)(F)F)C=1>>[Br:1][C:2]1[CH:3]=[C:4]([C:5](=[O:6])[CH3:20])[CH:11]=[C:12]([S:14]([F:19])([F:18])([F:17])([F:16])[F:15])[CH:13]=1

Participants

3

Reactant 2

HCID 441831181-[3-Methoxy-5-(pentafluorosulfanyl)phenyl]ethanoneHCID 581374643-Bromo-N-methoxy-N-methyl-5-(pentafluorosulfanyl)benzamide

Product 1

HCID 581374301-[3-Bromo-5-(pentafluorosulfanyl)phenyl]ethanone

Procedure

3-Bromo-N-methoxy-N-methyl-5-(pentafluorosulfanyl)benzamide (1.1 g) was converted and worked up analogously to 21d). Purification by means of HPLC was not necessary. 935 mg of the title compound were obtained.

Workup

  1. customPurification by means of HPLC

Sources & evidence

ORD record
ord-0638a360c6e0479685fe10f5a85c7df0
Source dataset
uspto-grants-2013_06
Patent number
US08466169B2

Reaction notes

Loading…