M-Phenylenediamine → HCID 86640289, compound

HRID 1258542Notes

Reaction equation

[C:1]1([NH2:8])[CH:6]=[CH:5][CH:4]=[C:3]([NH2:7])[CH:2]=1.[CH3:9][C:10]1[CH:18]=[C:17]([C:19]([F:28])([C:24]([F:27])([F:26])[F:25])[C:20]([F:23])([F:22])[F:21])[CH:16]=[CH:15][C:11]=1[C:12](Cl)=[O:13]>>[NH2:7][C:3]1[CH:2]=[C:1]([NH:8][C:12](=[O:13])[C:11]2[CH:15]=[CH:16][C:17]([C:19]([F:28])([C:20]([F:21])([F:22])[F:23])[C:24]([F:25])([F:26])[F:27])=[CH:18][C:10]=2[CH3:9])[CH:6]=[CH:5][CH:4]=1

Participants

Reactant 2

HCID 7935M-Phenylenediamine

HCID 17837208HCID 17837208, compound

Product 1

HCID 86640289HCID 86640289, compound

Procedure

N-(3-Amino-phenyl)-2-methyl-4-(1,2,2,2-tetrafluoro-1-trifluoromethyl-ethyl)-benzamide was prepared from benzene-1,3-diamine and 2-methyl-4-(1,2,2,2-tetrafluoro-1-trifluoromethyl-ethyl)-benzoyl chloride (Example I4) using the same procedure. 1H-NMR (CDCl3, 400 MHz): 7.6 (m, 1H), 7.52 (s, 2H), 7.40 (s, 1H), 7.30 (s, 1H), 7.13 (t, 1H), 6.72 (d, 1H), 6.50 (d, 1H), 3.76 (s, 2H), 2.24 (s, 3H) ppm.

Sources & evidence

ORD record: ord-4d1a728ad51e4b219fc7a2d971d84824
Source dataset: uspto-grants-2013_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08466180B2

Reaction notes

Loading…