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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1258634Generated: October 31, 2026

1,1'-Thiocarbonyldi-2(1H)-pyridone → HCID 86646343, compound

https://huagongshe.com/reaction/1258634

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1'-Thiocarbonyldi-2(1H)-pyridoneHCID 853162—
ReactantN-(3-amino-4-chlorobenzyl)pivalamideHCID 66765386—
SolventDichloromethaneHCID 6344—
ProductHCID 86646343HCID 86646343—

Reaction Steps

1,1′-Thiocarbonyldi-2-pyridone (2.12 g, 9.1 mmol) was added to a mixture of N-(3-amino-4-chlorobenzyl)-2,2-dimethyl-propionamide (2.00 g, 8.3 mmol) and DCM (60 mL) and stirred at rt for 1.5 h. The mixture was filtered over silica gel. The organic layer was concentrated to give the sub-title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08466186B2
Source datasetuspto-grants-2013_06
ORD IDord-7125d667e7ff480ebce03b54f597e544
Source noteuspto-grants-2013_06