反应详情

3-Acetylamino-2,4-dichloro-benzoic acid (21.0 g, 84.6 mmol) was stirred in 6 M aq. HCl-solution (120 mL) and acetic acid (250 mL) at reflux for 24 h. The reaction mixture was cooled, concentrated, diluted with water and concentrated again. The residue was diluted with water, stirred under cooling and filtered. The filtercake was washed and dried to give the sub-title compound.

1. temperatureThe reaction mixture was cooled
2. concentrationconcentrated
3. additiondiluted with water
4. concentrationconcentrated again
5. additionThe residue was diluted with water
6. temperatureunder cooling
7. filtrationfiltered
8. washThe filtercake was washed
9. customdried