HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 4-Chloro-5-(4-methyl-piperazin-1-yl)-2-nitro-N-methyl-aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 4,5-Dichloro-n-methyl-2-nitroaniline | HCID 289317 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-Chloro-5-(4-methyl-piperazin-1-yl)-2-nitro-N-methyl-aniline | HCID 44120649 | — |
Reaction Steps
The sub-title compound was prepared from N-methylpiperazine (200 mg, 2.0 mmol), 4,5-dichloro-N-methyl-2-nitroaniline (442 mg, 2.0 mmol) and potassium carbonate (304 mg, 2.2 mmol) in DMF (10 mL) in accordance to example 9 step (d).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08466186B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-492806d2163048e0a65034046d569426 |
| Source note | uspto-grants-2013_06 |