HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-methyl-2-nitro-4-(4-trifluoromethyl-piperidin-1-yl)-aniline → HCID 67957856, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-methyl-2-nitro-4-(4-trifluoromethyl-piperidin-1-yl)-aniline | HCID 67958090 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 67957856 | HCID 67957856 | — |
Reaction Steps
A mixture of N-methyl-2-nitro-4-(4-trifluoromethyl-piperidin-1-yl)-aniline (220 mg, 0.7 mmol), MeOH (7 mL) and Pd/C (30 mg) was stirred for 18 h at rt under a hydrogen atmosphere (3.0 bar). The catalyst was removed by filtration, the filtrate was concentrated and directly used in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08466186B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-59bd1007a75e4742a198fd0c4fca9248 |
| Source note | uspto-grants-2013_06 |