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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1258691Generated: November 3, 2026

Tetrahydrofuran → HCID 67957699, compound

https://huagongshe.com/reaction/1258691

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantHCID 44120656HCID 44120656—
SolventMethanolHCID 887—
ProductHCID 67957699HCID 67957699—

Reaction Steps

A mixture of 4-chloro-2-nitro-5-(4-trifluoromethyl-piperidin-1-yl)aniline (0.63 g, 1.9 mmol), THF (10 mL), MeOH (20 mL) and 50%-Pt-on-carbon (60 mg) was stirred for 22 h at rt under a hydrogen atmosphere (3 bar). The catalyst was removed by filtration and the mixture was concentrated to give the sub-title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08466186B2
Source datasetuspto-grants-2013_06
ORD IDord-b93fd3d83af74caba6a6b39b17106b45
Source noteuspto-grants-2013_06