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HRID1258732

反应详情

EQUATION

反应方程式

HRID 1258732 的结构方程式

REACTANTS

反应物

3
结构：CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[P-](F)(F)(F)(F)F
HCID2733084

Methanaminium, N-[(1H-benzotriazol-1-yloxy)(dimethylamino)methylene]-N-methyl-, hexafluorophosphate(1-) (1:1)

C11H16F6N5OP

结构：O=C(O)C1(C(F)(F)F)CC1
HCID2778306

1-(Trifluoromethyl)cyclopropane-1-carboxylic acid

C5H5F3O2

结构：Cl.NCc1ccc(F)c([N+](=O)[O-])c1
HCID53408003

1-(4-Fluoro-3-nitrophenyl)methanamine--hydrogen chloride (1/1)

C7H8ClFN2O2

PRODUCTS

生成物

1
结构：O=C(NCc1ccc(F)c([N+](=O)[O-])c1)C1(C(F)(F)F)CC1
HCID59529826

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

The sub-title compound was prepared in analogy to the procedure in Example 94, step (c) using 4-fluoro-3-nitro-benzylamine hydrochloride (3.0 g; 14.5 mmol), 1-(trifluoromethyl)-cyclopropanecarboxylic acid (2.5 g; 16.0 mmol), HBTU (6.07 g; 16.0 mmol), TEA (5.88 g; 58.1 mmol) and DMF (50 mL).