反应详情

The sub-title compound was prepared in analogy to Example 101, step (c) using 4-chloro-5-[5-chloro-1-methyl-6-(4-(trifluoromethyl)piperidin-1-yl)-1H-benzo[d]imidazol-2-ylamino]-2-fluorobenzonitrile (264 mg; 0.54 mmol), Ra—Ni (3 mg), H2 (5 atm) and THF (30 mL).