3-Amino-3-(3,4-dimethoxyphenyl)propanoic acid → Methyl 3-amino-3-(3-ethoxy-4-methoxyphenyl)propanoate

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Reaction Steps

The title compound was prepared following the method for preparing Intermediate 6 except that 3-amino-3-(3,4-dimethoxy-phenyl)propionic acid was substituted with 3-amino-3-(3-ethoxy-4-methoxy-phenyl)propionic acid. 1H NMR (CDCl3): δ 6.77-6.86 (m, 3H), 4.30 (s, 1H), 3.85 (t, 2H, J=5 Hz), 3.79 (s, 3H), 3.62 (s, 3H), 2.59 (s, 2H), 1.85 (d, 2H, J=5 Hz), 1.40 (s, 3H).

Provenance & Evidence