3-Amino-3-(3,4-dimethoxyphenyl)propanoic acid → Methyl 3-amino-3-(3-methoxy-4-propoxy-phenyl)propionate

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Reaction Steps

The title compound was prepared following the method for preparing Intermediate 6 except that 3-amino-3-(3,4-dimethoxy-phenyl)propionic acid was substituted with 3-amino-3-(3-methoxy-4-propoxy-phenyl)propionic acid. 1H NMR (CDCl3): δ 6.77-6.86 (m, 3H), 4.32 (q, 1H, J=5 Hz), 3.87-3.95 (m, 2H), 3.80 (s, 3H), 3.61 (s, 3H), 2.62 (d, 2H, J=5 Hz), 1.76 (s, 2H), 0.97 (t, 3H, J=6 Hz).

Provenance & Evidence