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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1258795Generated: October 31, 2026

3-Amino-3-(3,4-dimethoxyphenyl)propanoic acid → Methyl 3-amino-3-(3-methoxy-4-benzyloxy-phenyl)propionate

https://huagongshe.com/reaction/1258795

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-3-(3,4-dimethoxyphenyl)propanoic acidHCID 597182—
Reactant3-Amino-3-[4-(benzyloxy)-3-methoxyphenyl]propanoic acidHCID 5230283—
ProductMethyl 3-amino-3-(3-methoxy-4-benzyloxy-phenyl)propionateHCID 68471182—

Reaction Steps

The title compound was prepared following the method for preparing Intermediate 6 except that 3-amino-3-(3,4-dimethoxy-phenyl)propionic acid was substituted with 3-amino-3-(3-methoxy-4-benzyloxy-phenyl)propionic acid. 1H NMR (CDCl3): δ 7.26-7.44 (m, 5H), 6.75-6.94 (m, 3H), 5.13 (s, 2H), 4.35 (t, 1H, J=5 Hz), 3.89 (s, 3H), 3.61 (s, 3H), 2.59 (d, 2H, J=5 Hz), 1.84 (d, 2H, J=5 Hz)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08466191B2
Source datasetuspto-grants-2013_06
ORD IDord-e8c7ea99a62c4ef7b872aae6281e701f
Source noteuspto-grants-2013_06