Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 12588Generated: October 29, 2026

Trifluoroacetic acid → (R)-4-Amino-6-(4-heptyloxy-phenyl)-4-methyl-hexanoic acid

https://huagongshe.com/reaction/12588

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 58897684HCID 58897684—
SolventDichloromethaneHCID 6344—
Product(R)-4-Amino-6-(4-heptyloxy-phenyl)-4-methyl-hexanoic acidHCID 11772019—

Reaction Steps

To a stirred solution of (R)-4-tert-butoxycarbonylamino-6-(4-heptyloxy-phenyl)-4-methyl-hexanoic acid (24 mg, 0.06 mMol) in CH2Cl2 (2 ml) is added trifluoroacetic acid (0.1 ml). The mixture is stirred at RT for 6.5 hours. After that time, the reaction mixture is concentrated under reduced pressure to give the title compound as an amorphous white powder. The crude product is sufficiently pure to be used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07728020B2
Source datasetuspto-grants-2010_06
ORD IDord-0013bc2581a94e40a5eb4281af024df5
Source noteuspto-grants-2010_06