HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → (R)-4-Amino-6-(4-heptyloxy-phenyl)-4-methyl-hexanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 58897684 | HCID 58897684 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | (R)-4-Amino-6-(4-heptyloxy-phenyl)-4-methyl-hexanoic acid | HCID 11772019 | — |
Reaction Steps
To a stirred solution of (R)-4-tert-butoxycarbonylamino-6-(4-heptyloxy-phenyl)-4-methyl-hexanoic acid (24 mg, 0.06 mMol) in CH2Cl2 (2 ml) is added trifluoroacetic acid (0.1 ml). The mixture is stirred at RT for 6.5 hours. After that time, the reaction mixture is concentrated under reduced pressure to give the title compound as an amorphous white powder. The crude product is sufficiently pure to be used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07728020B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-0013bc2581a94e40a5eb4281af024df5 |
| Source note | uspto-grants-2010_06 |