3-Amino-3-methyloxetane → HCID 57377476, compound

Participants

Reaction Steps

As described for example 36b, 6-(4-(1-(4-fluorophenyl)-4-methyl-1H-1,2,3-triazol-5-yl)-1H-imidazol-1-yl)nicotinic acid (56 mg, 0.154 mmol) was converted, using 3-methyloxetan-3-amine instead of isopropylamine, to the title compound (57 mg, 86%) which was obtained as an off white solid. MS: m/e=434.3 [M+H]+.

Provenance & Evidence