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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1258922Generated: November 2, 2026

2-Amino-2-methyl-1-propanol → HCID 57377582, compound

https://huagongshe.com/reaction/1258922

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-2-methyl-1-propanolHCID 11807—
ReactantHCID 67956048HCID 67956048—
ProductHCID 57377582HCID 5737758279%

Reaction Steps

As described for example 36b, 6-(4-(1-(4-fluorophenyl)-4-methyl-1H-1,2,3-triazol-5-yl)-1H-imidazol-1-yl)nicotinic acid (65 mg, 0.178 mmol) was converted, using 2-amino-2-methyl-1-propanol instead of isopropylamine, to the title compound (61 mg, 79%) which was obtained as a white solid. MS: m/e=436.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08466181B2
Source datasetuspto-grants-2013_06
ORD IDord-4ec887212b6b4cb79a171a8a628df985
Source noteuspto-grants-2013_06