Pyrrole-2-carboxaldehyde → HCID 86652339, compound

HRID 1258954Notes

Reaction equation

HRID 1258954 reaction equation
[NH:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]=[O:7].Br[CH2:9][CH2:10][O:11][Si:12]([C:15]([CH3:18])([CH3:17])[CH3:16])([CH3:14])[CH3:13]>>[CH3:9][CH2:10][O:11][Si:12]([C:15]([CH3:18])([CH3:17])[CH3:16])([CH3:14])[CH3:13].[NH:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]=[O:7]

Participants

3

Reactant 2

HCID 13854Pyrrole-2-carboxaldehydeHCID 3608067(2-Bromoethoxy)-tert-butyldimethylsilane

Product 1

HCID 86652339HCID 86652339, compound

Procedure

1H-Pyrrole-2-carbaldehyde was alkylated with (2-bromoethoxy)(tert-butyl)dimethylsilane as described in Example 12, step 1 to provide 1-(2-ethoxy-tert-butyldimethylsilane-1H-pyrrole-2-carbaldehyde as a light yellow oil.

Sources & evidence

ORD record
ord-ee7e09ca5b9d45788e0c4a4b55516d20
Source dataset
uspto-grants-2013_06
Patent number
US08466193B2

Reaction notes

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