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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1259366Generated: October 29, 2026

Hydrochloric Acid → HCID 67193085, compound

https://huagongshe.com/reaction/1259366

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 67191802HCID 67191802—
CatalystZincHCID 23994—
SolventTetrahydrofuranHCID 8028—
ProductHCID 67193085HCID 6719308551%

Reaction Steps

Following the procedure set forth in Example 1 for the preparation of I-1g, 1-benzyl-7-(2-fluoro-4-iodo-phenylamino)-6-methyl-8-nitro-2,3-dihydro-1H-imidazo[1,2-a]pyridin-5-one (280 mg, 0.001 mol) in THF (30 mL) was reacted with zinc (211 mg, 0.003 mol) and HCl (1 mL) to afford 250 mg of the crude product which was used in the next step without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08466289B2
Source datasetuspto-grants-2013_06
ORD IDord-2361260a845c43948065904c96018fc0
Source noteuspto-grants-2013_06